Jorge Bermúdez played at the club level for several teams in Colombia including Deportes Quindío, América de Cali, Deportivo Quevedo, Deportivo Pereira and Independiente Santa Fe. He started his career with Deportes Quindio which was also the team he finished his career with 17 years later. Bermúdez also played for a number of clubs outside Colombia including Benfica (Portugal), Boca Juniors (Argentina), Olympiakos Pireus (Greece), Newell’s Old Boys (Argentina) and Barcelona Guayaquil (Ecuador). During his time with Boca Juniors he won a number of major titles including the Copa Libertadores and Copa Intercontinental in 2000 and three league titles (Ap 1998, Cl 1999 & Ap 2000). He was a participant at the 1992 Summer Olympics and went on to play 56 times for the full international squad including appearances at the 1998 FIFA World Cup and in three editions of the Copa América in 1995,1997 and 1999.